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AHA 2016: UF’s Larisa Cavallari presents findings on improving cardiac outcomes with genetic testing

Published: Nov 16th, 2016

This NIH-funded, UF-led study showed that a genetic test can significantly reduce the risk of adverse cardiac events for heart stent patients by helping identify the best antiplatelet medication for each patient.

Drug–drug and drug–gene interactions in a large population undergoing pharmacogenetic testing

Published: Feb 28th, 2016

As pharmacogenetic data are increasingly being incorporated into the patient care decision making process, additional information is needed to inform clinician strategies and priorities. An important step in obtaining these […]

TPMT genotyping: Decreased hematologic adverse events in IBD

Published: Feb 1st, 2016

Daniel Beylik, Pharm.D. Candidate, Class of 2016 Thiopurine agents such as 6-mercaptopurine or azathioprine are used in patients with inflammatory bowel disease (IBD) as well as some pediatric cancers (i.e., […]

American College of Medical Genetics revises position statement on direct-to-consumer genetic testing

Published: Jan 15th, 2016

In response to increasing availability of genetic testing opportunities and consumer demand, the American College of Medical Genetics (ACMG) has updated its 2008 position statement on direct-to-consumer genetic testing. In […]

Clopidogrel: Effect of esomeprazole on platelet activity, clinical outcomes

Published: Jan 15th, 2016

Daryl Nnani, PharmD Candidate 2016 Albany College of Pharmacy and Health Sciences Dual antiplatelet therapy with aspirin and clopidogrel is indicated for the prevention of atherothrombotic events in patients with […]

Celecoxib: CYP2C9 variability influences colorectal adenoma prevention

Published: Jan 4th, 2016

Daniel Beylik, Pharm.D. Candidate, Class of 2016 Celecoxib is a selective COX-2 NSAID. This agent has a potentially lower incidence of gastrointestinal adverse effects as compared with nonselective COX-2 inhibitors, […]

Informatics: Variability in EHR display of genomic data influences clinical use

Published: Jul 17th, 2015

Dyson Wake, PharmD As precision medicine advances and increasing amounts of genomic and genetic data are incorporated into the electronic health record (EHR), needs for storing, accessing, and displaying this […]

CPIC authors respond to CYP2D6–codeine clinical perspective article

Published: Jun 1st, 2015

The Clinical Pharmacogenetics Implementation Consortium (CPIC) published guidelines for use of codeine in patients with variable CYP2D6 metabolism in January 2014. These guidelines recommended a codeine alternative in CYP2D6 ultrarapid […]

New Lancet analysis supports benefit of pharmacogenomic testing for warfarin

Published: May 15th, 2015

CYP2C9 and VKORC1 genotypes identified individuals who required lower doses of warfarin and were more likely to be over-anticoagulated, according to a recent analysis of the ENGAGE AF–TIMI 48 trial […]

ASHP releases statement on pharmacist’s role in clinical pharmacogenomics

Published: Apr 1st, 2015

The American Society of Health System Pharmacists (ASHP) published a position statement on the pharmacist’s role in clinical pharmacogenomics in the April 2015 edition of the American Journal of Health-System […]